Learning Objectives: Hypothesis 1: How does it happen (sequence of events)? What are the contributing factors? Nutritional? Developmental? Inflammation? Why does this cause lameness? Hypothesis 2: What are the genetic factors influencing bone development? Breed disposition? Why does a malformed joint cause pain? What are contributing factors? Nutritional? Developmental? Inflammation? Hypothesis 3: How does inflammation cause pain? How does a joint get inflamed? What causes inflammation?