Specialty Exams Radiographs of the fetlock revealed soft-tissue swelling but no apparent damage to any bones. Localized infection of the joint is responsible for the increased opacity due to the large number of mononuclear cells that have migrated to the site. Abnormalities on the clinical pathology report included decreased hematocrit and hemoglobin values, an abnormally high platelet count, a large number of mononuclear cells and a good result for mucin. The first two findings (hematocrit and hemoglobin) cannot be supported by any other clinical findings; given their closeness to the reference interval, one can assume that the reported values are within the norm for this patient. The last three findings should be considered clinically significant for this case because they support the radiographic findings of localized infection. The high platelet count reflects increased platelet production to support the bodyÕs effort to wall off the localized infection. The mononuclear cells are chemotactically drawn to the joint to phagocytize bacteria and associated debris. The mucin and the elevated protein level further support the diagnosis that the infection is in its early stages because the mucin clot is good and the protein level is below 4 g/dl. Additionally, the joint fluid analysis showed pure positive growth of Klebsiella pneumoniae with sensitivity to amikacin, gentamicin, ceftiofur, chloramphenicol and enrofloxacin. In 50 percent of infectious arthritis cases, the culture and sensitivity are negative. Because this patient has a pure growth positive culture, we can conclude that this patient has infectious arthritis in the right hind fetlock.