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This Concept Map, created with IHMC CmapTools, has information related to: V06. Cystic Fibrosis, 6. CYSTIC FIBROSIS defect CF transmembrane conductance regulator gene (CFTR), Maintains hyrdration of secretions within airways/ducts especially in Lungs, CF transmembrane conductance regulator gene (CFTR) functions Maintains hyrdration of secretions within airways/ducts, Autosomal Recessive for white people q=1/25, chloride channel regulated by cAMP, Often azoospermatic due to Bad Wolfmann ducts, Breading ground for pathogens thus Recurrent inflammitory responses, chloride channel which Regulates other channels, Lung Disease this is Chief problem, 6. CYSTIC FIBROSIS phenotype Lung Disease, 6. CYSTIC FIBROSIS phenotype Bad first stool (meconium ilueus), Sweat Glands CF folks have Salty Sweat, Chief problem leads to Death usually by age 40, Retention of exocrine eenzymes leads to Fibrosis of pancreas, Lungs dehydration leads to Improper mucociliary clearance, Improper mucociliary clearance leads to Breading ground for pathogens, 6. CYSTIC FIBROSIS type Autosomal Recessive, 6. CYSTIC FIBROSIS phenotype Pancreatitis, 6. CYSTIC FIBROSIS etiology Predominately caucasians, Maintains hyrdration of secretions within airways/ducts through Excretion of Chloride