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This Concept Map, created with IHMC CmapTools, has information related to: Hemostasis disorders2, deficiency in factor VIII symptoms hematoma, thrombocytopenia though so PT and PTT are normal no coagulation factors involved, young women PENTAD OF TTP renal failure, vasculitis morphology NEED TO SEE VASCULAR DAMAGE, excessive consumption (DIC) KNOW THESE DISORDERS gram(+) sepsis, meningococcemia caused by Neisseria meningitidis direct damage via toxins, excessive consumption (DIC) organs involved CNS, D dimers tests for clot-associated FDP, decreased production bone marrow disorders drugs and toxins, excessive consumption (DIC) organs involved lung, secondary to disorder isoimmune thrombocytopenia post-transfusion thrombocytopenia, von Willebrand disease lab tests ristocetin cofactor assay: vWF activity, Henoch-Schonlein pupura (HSP) diagnosed childhood, red pulp of spleen ???? massive splenomegaly, inhibits protein C pupura non blanchable, RMSF infects endothelial cells lysis leads to petechial rash, fibrinolysis LOTS OF BLEEDING ????, increased destruction immune secondary to disorder, Henoch-Schonlein pupura (HSP) autoimmune, hypersensitivity IgA-mediated, hypersensitivity Ag-Ab complexes formed ????