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This Concept Map, created with IHMC CmapTools, has information related to: Untitled 1, Jmjd2c Loss Leads to Loss of Demethylation, Activate and Repress Genes as Transcription Factors Shared Targets REST, Sox2 Functions to Activate and Repress Genes as Transcription Factors, Inner Cell Mass Interaction with ICM & Epiblast produces Extraembryonic Ectoderm, Maternal genes Development Controlled by Embryonic genes, Activate and Repress Genes as Transcription Factors Nanog Targets Nrob1, Jmjd2c Regulate Targets by Demethylation of Histone H3K9, All other adult cell types For example Endoderm, Embryonic genes Celularization/ Differentiation Inner Cell Mass, Trophoectoderm Fates limited to trophoblast components of placenta, Tcl1 Overexpression Rescues from, Activate and Repress Genes as Transcription Factors Oct4/Sox2 Targets Dkk1, Activate and Repress Genes as Transcription Factors Shared Targets Sox2, All other fetal cell types Forms All other adult cell types, Pou5f1 Encodes for Oct4, Activate and Repress Genes as Transcription Factors Nanog Targets Bmp4, Oct4 Functions to Activate and Repress Genes as Transcription Factors, Rescues from Loss Leads to Loss of Demethylation, Extraembryonic Ectoderm Which houses Trophoblast stem cells, All other fetal cell types Forms ES, EG, EC cells