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This Concept Map, created with IHMC CmapTools, has information related to: O'dea, Macrophage present antigen to CD4+ T cells, Smoking history leads to Mucociliary dysfunction, Acute Phase Response causes release of CRP, Pt O'Dea 39 y.o. Caucasian male has Sputum culture negative for pathogenic bacteria, Antibiotic resistance to Antibiotic therapy (amoxicillin), C3a leads to Peripheral leukocytosis "left shift" (produced in bone marrow), CRP leads to Fever and chills, bacterial lysis triggers recruitment of CD4+ T cells, Sputum culture negative for pathogenic bacteria suggestive of Strep pneumoniae due to inability to be cleared, Inflammatory Response lead to Consolidation, elevated CRP lead to the diagnosis of Community acquired pnemonia, anaphylatoxin include C3a, Sputum culture negative for pathogenic bacteria lead to the diagnosis of Community acquired pnemonia, Il-1 leads to Inflammatory Response, IgG3 leads to neutralization, Complement Result in Membrane Attack Complex (MAC), Persistant productive cough lead to the diagnosis of Community acquired pnemonia, Pneumococcal virulence factors (capsule, pneumolysin, autolysin) contains Pneumolysin, Strep pneumoniae due to inability to be cleared has Antibiotic resistance, mature bacteria cells triggers recruitment of Macrophage