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This Concept Map, created with IHMC CmapTools, has information related to: Hypertension, Hypertension - Stage I Neurohormonal Effect Renin Angiotensin Aldosterone System, Cardiovascular Disease Affected by SNS stimulatory Consequences, Hypertension - Stage I Pharmacologic treatment Angiotensin II Receptor Blockers, Thiazide Diuretics Examples Chlorthalidone, Lifestyle Treatment options Manage stress, Patient ???? 33 y/o African American Male, Proximal Reabsorption Risk Hypercalcemia, Distal Convoluted Tubule of the kidneys To Block Sodium-chloride transporter, Alpha Receptors Effects Vasoconstriction, SNS stimulatory Consequences Physiologic Effects Platelet activation; Hemostatic changes; Hemocentration, Renal blood flow Decrease GFR, Cardiovascular Effects Sympathetic NS Beta 1 Receptors, Angiotensin II Physiologic Effects Aldosterone release, Angiotensin II Physiologic Effects Increase blood volume, 145/95 & 149/97mmHg Indicates Cardiovascular Disease, Increased excretion of sodium chloride (and magnesium) and therefore water Risk Hyponatremia, 33 y/o African American Male Blood Pressure Results 145/95 & 149/97mmHg, Angiotensin Converting Enzyme Inhibitors Angiotensin-Converting Enzyme forms Angiotensin II, Increased excretion of sodium chloride (and magnesium) and therefore water Risk Hypomagnasemia, Hypertension - Stage I Pharmacologic treatment Calcium Channel Blockers