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This Concept Map, created with IHMC CmapTools, has information related to: Overzicht alle cmaps v4.8, Ras- GTP activeert PI3K, FOXO remt Differentiatie Overleving, CDKN2A expressie p14, Rac activeert Rho, alfa-catenine zorgt voor dynamisch evenwicht actine filamenten, mTOR activeert s6k1, Focal adhesion turn over leidt tot Migratie, P53 expressie p53, TNFα Bindt TNFR1, MMP activeert PDGF, co-Smad + R-Smad complex activeert P21/CDKN1A, WNT Bindt en activeert Frizzled, Transcriptie van WNT-genen onder andere LEF1, B-Raf fosfolyeert MEK 1/2, VEGFR 1/2 activeert SRC/VRAP, fos vormen AP-1, D-Cycline vormt D-cycline cdk6 complex, MAPK reguleert transcriptie, p16 remt Cdk 4, co-Smad + R-Smad complex activeert P15/CDKN2B