Warning:
JavaScript is turned OFF. None of the links on this page will work until it is reactivated.
If you need help turning JavaScript On, click here.
This Concept Map, created with IHMC CmapTools, has information related to: 18. Shuttles, Oxaloacetate Can be reduced to Malate, Glycerol-3- Phosphate both Can cross inner membrane, Metabolites including Oxaloacetate, Inner Mitochondrial Membrane is impermeable to many things so, issue becomes "How to keep thngs balanced", Aspartate reversible Oxaloacetate, "How to keep thngs balanced" answer Use redox potentials as needed, Use redox potentials as needed mechanisms Malate-Aspartate Shuttle, Enz: Glycerol-3-phosphate Dehydrogenase in cytosol Uses NAD/NADH, Malate which can Cross the inner membrane, Enz: Glycerol-3-phosphate Dehydrogenase reduced to Glycerol-3- Phosphate, SHUTTLES important because Inner Mitochondrial Membrane is impermeable to many things, Enery difference ie. FADH2 worth 1.5 ATP, Inner Mitochondrial Membrane is impermeable to many things including Metabolites, Enz: Glycerol-3-phosphate Dehydrogenase oxidized to DHAP, Enz: AST (GOT) can undergo amino transferase to Aspartate, DHAP reduced to Glycerol-3- Phosphate, Inner Mitochondrial Membrane is impermeable to many things including NADH, Cross the inner membrane and Can be reversed, Malate-Aspartate Shuttle involves Oxaloacetate, Glycerol phosphate Shuttle involves DHAP