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This Concept Map, created with IHMC CmapTools, has information related to: 30a4. Follicular Atresia, At any stage although Multiple graafian follicles during menstral cycle, FOLLICULAR ATRESIA can occur... At any stage, Ovaries of Female reproductive system, FOLLICULAR ATRESIA histologic indications LARGE MULTILAMINAR, SECONDARY, GRAAFIAN -Granulosa cells become loosened and frayed -Granulosa hypertrophy and apoptosize -Gap junctions between oocyte & granulosa are lost -Zona pellucida is persists for a while (last structure), -Desmosomes break up Causes -Collapse -Invasion of connective tissue side note Granulosa cells have -Desmosomes -Gap Junctions -No Tight Junctions, Follicles of Ovaries, -Desmosomes break up Causes -Collapse -Invasion of connective tissue see Cell junctions (CaTOS-1), FOLLICULAR ATRESIA of Follicles, FOLLICULAR ATRESIA Reference Pages 1254-1255, Granulosa cells have -Desmosomes -Gap Junctions -No Tight Junctions just like Epidermis? (CaTOS-2), FOLLICULAR ATRESIA histologic indications ATRESIA OF PRIMARY FOLLICLES -Hard to tell, LARGE MULTILAMINAR, SECONDARY, GRAAFIAN -Granulosa cells become loosened and frayed -Granulosa hypertrophy and apoptosize -Gap junctions between oocyte & granulosa are lost -Zona pellucida is persists for a while (last structure) -Desmosomes break up Causes -Collapse -Invasion of connective tissue, Granulosa cells have -Desmosomes -Gap Junctions -No Tight Junctions see Cell junctions (CaTOS-1)