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This Concept Map, created with IHMC CmapTools, has information related to: Anti-inflammatories for Swollen Joint, Dexamethasone side effects Polyuria, Cyclo-oxygenase including isoforms COX-1, Inflammatory including Autoimmune, Dexamethasone side effects Muscle wasting, Corticosteroids mechanisms Corticosteroid Receptor Modulates Nuclear Transcription, Corticosteroid Receptor Modulates Nuclear Transcription suppress Pro-inflammatory Mediators, Ubiquitous ???? Constitutive, Prednisone side effects Polydipsia, Dihydrofolate Reductase blocking DNA synthesis & Cell Division, Autoimmune e.g. Lupus, COX-2 is Inducible, NSAIDs e.g. Aspirin, Thermotherapy Tx Inflammatory, CNS presumably by Elevating Pain Threshold (possibly NO), Metabolic e.g. Pseudogout, Inflammation chracterized in 100 A.D. as Loss of function, Prostaglandin Synthesis from Arachadonic Acid, COX-2 actions Antipyretic, Corticosteroid Receptor Modulates Nuclear Transcription promote Inhibitors, Cyclo-oxygenase including isoforms COX-2