SLE is defined by a
chronic autoimmune disease targeting connective tissues and DNA.
SLE has multi-system affects including the heart, lungs,
joints, blood vessels, skin, liver, and nervous system.
An exact cause of SLE is
not known, however individuals with HLA-DR2 and HLA-DR3 genes are
more susceptibleto
SLE. SLE is commonly a type III hypersenstivity reaction.