Group 15: SA O seq Clinical Signs/symptoms: A segment of dead bone or foreign material within the bone elicits a focal infection which causes increased pressure within the bone. Cloaca are found in the bone near the sequestrum which are connected to fistulous tracts to the skin surface which usually drain pus. Intermittent or persistent lameness, possible atrophy, local pain, fluctuant swellings, periodic febrile episodes and inappetence. History: History of sepsis or surgery are important considerations. Exogenous contamination is the most important route of infection in adult animals, ie: fractures, gunshot wounds, puncture wounds, etc. Clinical observations: Physical exam findings: Draining tracts surrounding infected bone, lameness in the affected limb, pain elicited upon palpation, Specialty exams: Radiographs-should see radiodense area with radiolucent area surrounding it. -also see bone proliferation with smooth rounded edges and sclerotic densities -may see bone destruction or bone remodling depending on the infective bacteria Culture-positive culture can be obtained from involved bone. Management plan: Local and systemic treatment is necessary; culture, identification, and sensitivity tests are needed before antibiotic treatment begins. A temporary anti-infective should be used until the sensitivity testing is completed. Surgery to remove sequestrum, stabilization of bone following surgery is necessary. Prognosis: Guarded until dead bone or sequestrum is removed, then the prognosis is good. How and why is situation different from or similar to the case 3 situation? Harder to cure because bacteria is more isolated and antibiotics are not effective. Draining tracts are present