Management Plan Septic arthritis and osteomyelitis is an emergency for this foal, and needs to be treated immediately. We are going to treat the foal aggressively with systemic antibiotics. Our choice is an amikacin/potassium penicillin combination. The Klebsiella pneumoniae that was cultured is sensitive to the amikacin, and penicillin is a good broad spectrum antibiotic for gram positive organisms. Even though the Klebsiella was cultured, it may have been a contaminant, so the penicillin will help cover the bases. The filly may need long-term treatment (4-6 weeks), and she will be on the antibiotic for at least 2 weeks. We will also lavage the joint with Normasol. The procedure will be tried with sedation and local anesthesia first. The joint will be infiltrated with the solution via needle, and also drained by needle. Local perfusion with antibiotics (amikacin) in the fetlock region of the right hind will be performed. We will use a tourniquet to occlude blood flow and inject the antibiotic into a local vessel, for example, the plantar metatarsal artery or vein. This procedure will be performed every other day while the filly is in the hospital. The filly will also receive phenylbutazone to decrease inflammation and relieve pain. After these procedures, the leg will be wrapped to give the filly some support and to help prevent further infection. In consideration for the finances or our client, this is our first plan of action. The filly needs stall rest or restriction from exercise (a small paddock) for several weeks to months. This will give her tissues time to rest and respond to treatment. After she has begun to recover, her joint should be passively flexed at least once a day to maintain range of motion and help rehabilitate the joint. If the filly does not respond, there are other courses of action available if the client wishes to pursue them. Surgery to open the joint, curettage the affected bone, and flush the joint may help the filly. Antibiotics could also be administered via the intramedullary cavity through a hole drilled in the bone. This option would be an alternative to the regional perfusion.