Diagnosis Our diagnosis, based on signalment, history, physical exam, and specialty tests, is that Titan has a congenital medial patellar luxation of the right rear leg. This was worsened by trauma from jumping off the bed and probably by playing with the larger dog more recently. The grade of the luxation is probably a Grade II, based on the fact that it is an intermittent non-weight bearing lameness. A Grade II patellar luxation is described as a patella that can dislocate spontaneously or can be pushed out, but can stay within the trochlear groove. Pathophysiology Patellar luxation usually describes an unstable patella that has a tendency to move either medially or laterally over the femoral trochlear ridge. In a normal dog, the patella is well-seated in the trochlear groove. The normal patella is usually hard to differentiate from the ridges of the trochlea. The longitudinal axis of the quadriceps muscle, patella, patellar ligament, trochlea, and tibial tuberosity should be in a straight line. Patellar instability is best evaluated when the stifle joint is in extension. Congenital medial patellar luxation is a hereditary disease affecting small breed dogs most commonly. The small breeds most affected by this disease are miniature and toy Poodles, Pomeranians, Yorkshire Terriers, Pekingese, Boston Terriers, and Chihuahuas. Medial luxation of the patella is also more common than lateral patellar luxation. Congenital luxation is usually evident by 4 to 6 months of age, although minor deformities can occur later in life. Traumatic luxation or grade I and grade II luxations can present at any age. Most dogs with medial patellar luxation have some form of related structural deformity and may have a bow-legged appearance. The pathophysiology of congenital medial patellar luxation is controversial. These changes seem to start in the hip, but are reflected throughout the limb. The following paragraph is a list of musculo-skeletal abnormalities associated with medial patella luxation. Coxa vara, or a reduction of the inclination (normal inclination angle is 135), is usually a part of the underlying deformity with medial patellar luxation. Lateral torsion of the distal femur, usually from a deforming force at an angle to an active growth plate, can also be associated with patellar luxation. Medial displacement of the quadriceps muscle group can occur from the lateral torsion of the distal femur. This also is associated with patellar luxation. Lateral bowing of the distal one-third of the femur resulting in an S-shaped conformation with tilting of the joint because of abnormal pressure. A shallow trochlear groove, from less patellar pressure than normal on the trochlear groove, can cause a failure of the patella to articulate properly with the trochlea. Dysplasia of the femoral epiphysis, rotational instability of the stifle joint, tibial deformities, and degenerative joint disease are other deformities that may occur from abnormal pressure on the growth cartilage of the epiphysis or abnormal wear and tear on the articular surfaces, resulting in patellar luxation. The deformities listed above can range from severe to mild. The mild cases may not always be seen on radiographs, but palpation of the patella should result in manual or permanent luxation. The age of the patient and the permanency of the luxation also play a role in the pathophysiology of patellar luxation. The younger the animal and the less often the patella luxates, the milder the case.