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This Concept Map, created with IHMC CmapTools, has information related to: Section 3.4, immortalization of mesodermal cells, Shope papillomavirus cause papillomas, mouse polyomavirus form class of viruses called papovaviruses, DNA viruses e.g. mouse polyomavirus, cancer such as a benign skin lesion called papillomas, DNA viruses can induce cancer, Shope papillomavirus form class of viruses called papovaviruses, SV40 virus which is further described in Section 3.6, DNA viruses e.g. SV40 virus, SV40 virus causes immortalization, nonpermissive hosts thus virus pursued a lytic cycle, mesodermal cells thus may be the etiological agent of the mesothelioma plague, vacuoles thus the infected cells were permissive hosts, SV40 virus may form fluid-filled bubbles in infected cells called vacuoles, SV40 virus may infect nonpermissive hosts, SV40 virus form class of viruses called papovaviruses, cancer thus may be called tumorigenic, DNA viruses e.g. Shope papillomavirus