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This Concept Map, created with IHMC CmapTools, has information related to: Section 3.5, transformed cells which have tumorigenicity, tumors only if bypassed by the immune system, tumor rejection thus does not allow xenografting, immunocompromised e.g. nude mice, immunocompromised which allows xenografting, tumor viruses induce multiple changes in phenotype, tumor rejection which is further discussed in Chapter 15, transformed cells which are immortalized, immortalized which is further discussed in Chapter 10, tumorigenicity which means they can generate tumors, tumors experience tumor rejection, immune system such as when it is immunocompromised, tumor rejection i.e. when tumor cells are injected into mice subcutaneously, transformed cells which are anchorage-independent, normal cells causing them to become transformed cells, normal cells which are anchorage-dependent, tumor rejection when attacked by the immune system, tumorigenicity occurs when host cells and injected cells are syngeneic, phenotype of normal cells