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This Concept Map, created with IHMC CmapTools, has information related to: Chapter 3-5, immortalization as discussed in Chapter 10, immunocompromised lack functional imune system, normal cells are anchorage dependent, phenotype including loss of contact inhibition, tumor viruses induce changes, nude mice lack hair, changes in phenotype, under the skin aka subcutaneously, phenotype including tumorigenicity, phenotype including immortalization, immunocompromised ex nude mice, phenotype including anchorage-independence, immunocompromised accept tissues from other species, anchorage-independence ability to multiply without attachment to solid, anchorage dependent absolute requirement for attachment to solid, immunocompromised used for tests of tumorigenicity, tissues from other species aka xenografts, tissues from other species injected under the skin