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This Concept Map, created with IHMC CmapTools, has information related to: Section 4.6, protein receptor EGF cannot bind regulatory ligands, structural changes which are further described in Chapter 5, protein receptor EGF expressed from ras gene, protein receptor EGF thus acts as an oncoprotein, structural changes in proteins, ras gene caused by point mutation, bcl-abl translocation which has two different reading frames, proteins such as hybrid proteins, hematopoietic malignancies e.g. chronic myelogenous leukemia, hybrid proteins e.g. caused by bcl-abl translocation, proteins such as decapacitation, bcl-abl translocation causes hematopoietic malignancies, decapacitation as seen in protein receptor EGF