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This Concept Map, created with IHMC CmapTools, has information related to: Ch.5 merged revised, paracrine signalling eg signal close cells, growth factors can also stimulate Motility, tissue architecture depends on discarding, Dishevelled protein inhibits GSK-3β, Her2 is a TK, growth factor receptor can function as a TK, Altered Ras is found in a variety of tumors, anchorage dependence attach to ECM, signal-transducing proteins funnel signals into the nucleus, Protein structural changes affect the firing of Kit, Hematopoiesis is the formation of various types of blood cells, EGF bind specifically to the EGF-R, growth factors can contain mutations, kinase eg transferer of phosphate group, TGF-β receptors phosphorylate threonine, EGF-R as mentioned in Section 4.6, autocrine signalling eg cell self-signalling, induces endocytosis of Her2, GAPs for hydrolysis of GTP, serpentine contribute to few cancers