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This Concept Map, created with IHMC CmapTools, has information related to: Section 6-10, Axin help GSK-3β bind β-catenin, Undifferentiated cells discussed further in Chapter 7, Cadherins form attachments to the Extracellular matrix, Cyclin D1 when phosphorylated is a target for Ubiquitylation, Glycogen synthase kinase-3β (GSK-3β) phosphorylates Cyclin D1, Wnt indirectly deactivated by Glycogen synthase kinase-3β (GSK-3β), Cadherins can associate with one another to form Adherens junctions, Cyclin D1 discussed further in Chapter 8, Tcf/Lef promotes the transcription of myc gene, Tcf/Lef promotes the transcription of Cyclin D1, Cadherins bind β-catenin, Tcf/Lef are Transcription factors, Extracellular matrix similar to Integrins, Ubiquitylation results in Protein degradation, β-catenin when phosphorylated is a target for Ubiquitylation, myc gene discussed further in Chapter 8, β-catenin binds to and activates Tcf/Lef, Adenomatous polyposis coli protein (Apc) help GSK-3β bind β-catenin, Glycogen synthase kinase-3β (GSK-3β) phosphorylates β-catenin, β-catenin concentrations can result in Undifferentiated cells