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This Concept Map, created with IHMC CmapTools, has information related to: Section 6-11, Small-cell lung carcinomas synthesize Neuropeptides, β sub-unit when activated form a βγ-heterodimer, γ sub-unit when activated form a βγ-heterodimer, βγ-heterodimer when activated activates Src, Phospholipase C-β cleaves from some membrane phospholipids Inositol (1,4,5)-triphosphate (IP3), α sub-unit is inactivated when it binds GDP, α sub-unit when activated separates from γ sub-unit, α sub-unit when activated activates Adenylyl Cyclase, Heterotrimeric G-proteins are composed of α sub-unit, α sub-unit is activated when it binds GTP, βγ-heterodimer when activated activates Phospholipase C-β, α sub-unit when activated activates Phospholipase C-β, Cyclic AMP are powerful Secondary messengers, α sub-unit when activated separates from β sub-unit, G-protein-coupled receptors bind as ligands Neuropeptides, βγ-heterodimer when activated activates Phosphatidyl inositol-3 kinase (PI3K), Heterotrimeric G-proteins are composed of γ sub-unit, G-protein-coupled receptors bind Heterotrimeric G-proteins, Inositol (1,4,5)-triphosphate (IP3) are powerful Secondary messengers, Small-cell lung carcinomas can establish Autocrine signaling