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This Concept Map, created with IHMC CmapTools, has information related to: Section 7-5, Section 10.4 discusses mechanisms, mechanisms can cause LOH, mutations of Rb gene, Chapter 8 will discuss Rb gene, chromosomal localization of Rb locus, hemizygosity occurs when nondisjunction, zymograms show LOH, LOH at the Rb locus, nondisjunction can cause LOH, LOH of Rb gene, zymograms separate isoforms