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This Concept Map, created with IHMC CmapTools, has information related to: Chapter 6, Ras oncoproteins causing tumor cells, nucleus may be carried out via concentration, Ras genes with point mutations, integrin signaling undergo convergence, negative feedback loops caused by conformational changes, negative feedback loops caused by protease activity, integrin signaling bind ligands, signal transduction specificity is facilitated by specific binding SH2 domains, point mutations may affect its reading frame, signal transduction specificity is facilitated by specific binding SH3 domains, Ras signaling pathways begins with Ras protein, nonamplification e.g. Notch receptor, intrinsic activity e.g. noncovalent modification, nucleus may be carried out via localization, signal transduction from cell surface, beta-catenin anchors to ECM, covalent modification e.g. phosphorylation, signal transduction is carried out by signal molecules, signal transduction e.g. integrin signaling, transcription may include delayed early genes