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This Concept Map, created with IHMC CmapTools, has information related to: Section 9-5, p53 causing cytostatic, genotoxic signals ex irradiation, p53 has downstream effects, p53 induces expression of p21^Cip1, genotoxic signals induce p53, p53 is normally labile, genotoxic signals are cytostatic, hyperactive causes premature aging, p53 when hyperactive, genotoxic signals ex DNA damage