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This Concept Map, created with IHMC CmapTools, has information related to: Section 9.11, Tsp-1 is a secreted protein, Tsp-1 functions in the extracellular space, p53 inactivation provides advantage to incipient cancer cells, Tsp-1 will be discussed in Chapter 13, incipient cancer cells includes many steps, p53 inactivation causes telomere collapse, Tsp-1 blocks development of blood vessels, formation of incipient cancer cells, telomere collapse will be discussed in Chapter 10