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This Concept Map, created with IHMC CmapTools, has information related to: Section 11.3, APC loss causes trapping, colonic crypts have a rapid cell death inducing organization, APC loss occurs early in colonic growths, genetic alterations during tumor progression, genetic alterations ex LOH, colonic growths can take many genetic paths, colonic growths accumulate genetic alterations, LOH of TSGs, LOH in various chromosomal arms, tumor progression can take many genetic paths, trapping of cells in the colonic crypts, Barrett's esophagus can take many genetic paths