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This Concept Map, created with IHMC CmapTools, has information related to: Section 11-12, transformation requires 5 intracellular pathways, human tumors don't reveal the identities, identities of proteins, transformation can be achieved by blocking PP2A, mammalian body size may be correlated to transformation, human cells are constructed to be highly resistant to immortalization, malignancies as will be discussed in Chapter 14, human cells are constructed to be highly resistant to transformation, genes that program malignancies, proteins that program malignancies, identities of genes, human tumors confounds understanding of transformation, immortalization can be achieved by blocking PP2A, PP2A is heterotrimeric, genetics of human tumors, PP2A in an extremely complex holoenzyme