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This Concept Map, created with IHMC CmapTools, has information related to: Section 13.10, refractory tumors as will be discussed in Chapter 16, refractory tumors which may outsmart anti-angiogenesis therapies, radiotherapy is an anti-angiogenesis therapies, Gleevec is a PDGF-R inhibitor, anti-angiogenesis therapies kill normal cells, anti-angiogenesis therapies could treat cancer, anti-angiogenesis therapies treat islet cell carcinogenesis, anti-cancer drug development forms refractory tumors, anti-angiogenesis therapies ex Gleevec, asmase-negative mice have shown that radiotherapy, Gleevec as will be discussed in Chapter 16, anti-cancer drug development as will be discussed in Chapter 16, wild-type mice have shown that radiotherapy