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This Concept Map, created with IHMC CmapTools, has information related to: 02i. Influenza Virus, INFLUENZA VIRUS bug Causes damage to resp. epithelium, Drift = small changes (usually in H or N) that causes new strains can occur in Flu B, Symptoms Reye's Syndrome -Aspirin, Causes damage to resp. epithelium Necrosis, Leads to cytokine release responsible for Symptoms, INFLUENZA VIRUS Treatment, Adherence through sialic acidi on host Can bind to RBC's, Causes damage to resp. epithelium Destruction of cilia can lead to 2nd infections, INFLUENZA VIRUS bug Non structural proteins, Diagnosis Serology not too useful, INFLUENZA VIRUS Epidemiology Transfer of droplets from person to person, Vaccines Dr. Elder stresses we should get them\, Cough from destruction of epith. Becomes more prominent later on in illness, INFLUENZA VIRUS Epidemiology Sall outbreaks every 2-3 years -Begin abruptly -End after 2-3 weeks (why? who knows), INFLUENZA VIRUS Epidemiology Pandemics every 30 years (we're overdue for one), Hemagglutinin Adherence through sialic acidi on host, Symptoms Abrupt onset, INFLUENZA VIRUS Epidemiology Shift vs Drift, Symptoms Deaths highest in elderly or those with CV disease, Zanamivir, Oseltamir good in conjunction with Vaccines