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This Concept Map, created with IHMC CmapTools, has information related to: Anti-inflammatories for Swollen Joint, Dexamethasone side effects Polyuria, Dexamethasone side effects Muscle wasting, Inflammatory including Autoimmune, Cyclo-oxygenase including isoforms COX-1, Corticosteroid Receptor Modulates Nuclear Transcription suppress Pro-inflammatory Mediators, Corticosteroids mechanisms Corticosteroid Receptor Modulates Nuclear Transcription, Ubiquitous ???? Constitutive, Dihydrofolate Reductase blocking DNA synthesis & Cell Division, Prednisone side effects Polydipsia, Autoimmune e.g. Lupus, Thermotherapy Tx Inflammatory, NSAIDs e.g. Aspirin, COX-2 is Inducible, CNS presumably by Elevating Pain Threshold (possibly NO), Inflammation characterized in 100 A.D. as Loss of function, Metabolic e.g. Pseudogout, COX-2 actions Antipyretic, Prostaglandin Synthesis from Arachadonic Acid, Cyclo-oxygenase including isoforms COX-2, Corticosteroid Receptor Modulates Nuclear Transcription promote Inhibitors