WARNING:
JavaScript is turned OFF. None of the links on this concept map will
work until it is reactivated.
If you need help turning JavaScript On, click here.
This Concept Map, created with IHMC CmapTools, has information related to: therapy for pesticide and drug poisoning - general treatment, overall strategy for treatment of poisoned pt ???? within 1hr 1. gut decontamination, overall strategy for treatment of poisoned pt ???? usu after absorption 2. enhancing elimination of toxin, usu after absorption 2. enhancing elimination of toxin ???? 1. serial activated charcoal (only removes drugs subj to enterohepatic and enteroenteric recirculation; e.g. CAH, paraquat, theophylline, & phenobarbital) 2. hemodialysis - blood pumped through dialysis membrane pores. cell & plasma proteins retained - good only for sm toxins (MW < 500) w/ high water solubility, and low protein-binding (e.g. treating methanol poisioning) 3. hemoperfusion - blood pumped through charcoal filter cartridge (e.g. paraquat, theophylline, phenobarbitol, salicylate), overall strategy for treatment of poisoned pt ???? 3. use specific antidotes and other supportive therapy, within 1hr 1. gut decontamination ???? 1. emesis (ipecac syrup) 2. gastric lavage (endotracheal tube and orogastric tube) 3. actvd charcoal, given w/ cathartic (laxative - sorbitol or Mg sulfate) (bind to v large surface area. 1g = 3000m^2) -- molecules w/ lrg surf area bind -- -- molecules w/ sm surf area don't bind --