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This Concept Map, created with IHMC CmapTools, has information related to: imm9 humoral immune response 3, isotype switching allows expression beyond IgM, IgD. i.e. IgA,IgE, IgG, T-helper cells regulate isotype switching, antigens stimulate T-helper cells, Where do T- and B-cells interact? ans lymph node, B-cell surface receptor antigen endocytosed ????, B-cell surface receptor bind Ag