Goodpasture's Syndrome                                      Goodpasture's Syndrome is a nephrotic disease charaterized by autoantibodies directed against the collagen in basement membrane of the glomerulus.  These autoantibodies are specific for the alpha-3 regions of type IV collagen. This condtion is more common men and 75 percent already posses HLA type DR15 or DR4. Symptoms and clinical Signs: Shortness of Breath pallor burning sensation while urinating blood in urine BUN and Creatinine levels increased Increased Urine Protein   Credit: Kim Le