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This Concept Map, created with IHMC CmapTools, has information related to: 10.18 CBL - Organophosphate, Oscar Perham objective findings include Hyperactive bowel sounds, increased Ca++ concentration resulting in contraction of bladder and intestinal walls, increased Ca++ concentration resulting in Excess contraction of ciliary muscle of eye, Oscar Perham objective findings include Hypotension, preganglionic autonomic neurons causing overstimulation of postganglionic sympathetic neurons in eccrine glands, postganglionic parasympathetic neurons leads to overstimulation of M3- cholinergic receptor, Acetylcholinesterase then leads to accumulation of ACh, organophosphate which phosphorylates Serine Hydroxyl group on AChase, Oscar Perham presents with Blurred Vision, preganglionic autonomic neurons causing overstimulation of postganglionic parasympathetic neurons, Excess contraction sphincter muscle of eye leading to uncontrolled constriction of pupil, CNS neurons possibly causing coma, Organophosphate Poisoning treated with Pralidoxime, M3- cholinergic receptor results in activation of PLC, preganglionic autonomic neurons causing overstimulation of somatic neuromuscular junction, CNS neurons possibly causing lethargy, Oscar Perham objective findings include Lacrimation, Pralidoxime dephosphoraylates Serine Hydroxyl group on AChase, Atropine which is a muscarinic Ach receptor antagonist, relaxation of bladder and intestinal sphincter contributing to Urinary incontinence