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This Concept Map, created with IHMC CmapTools, has information related to: 12.6 Syncope (Round 2), unable to relax without drinking" which indicates alcohol dependence, capillaries and/or lymphatic channels into tissue, sensitivity of myofilaments causing Ca++, tissue commonly caused by increased capillary hydrostatic pressure, alcohol dehydrogenase (in cytosol) which forms acetaldehyde, acetaldehyde which can lead to increased ROS production, compensatory increase in preload leading to increased End diastolic volume, inability to practice according to accepted standards due to substance use is a characteristic of impaired physician, increased capillary hydrostatic pressure resulting in Pulmonary edema, increased ROS production can act as ETC uncoupler, 1 bottle of wine/night on weekdays (if not on call) which indicates alcohol dependence, decreased cardiac contractility due to decreased release of Ca2+ release from SR, tachycardia leading to Increased end systolic volume, tissue commonly caused by lymphatic channel obstruction, Dilated left atrium and ventricle consistent with Dilated Cardiomyopathy, alcohol dependence is a characteristic of impaired physician, decreased ATP production contributing to decreased cardiac contractility, Ejection fraction of 26% causing CHF, Alcohol abuse reports unable to relax without drinking", near-syncope contribute to inability to practice according to accepted standards due to substance use