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This Concept Map, created with IHMC CmapTools, has information related to: Week 19 Immuno, Histmaine causes SM contraction, Degranulation releasing GM-CSF, Il-4 initiate Class-Switching, Sensitization by extraction of Initial Antigen, Degranulation releasing Il-4, Basement Membrane Degradation leads to Inflammation, Degranulation releasing Heparin, TNF-alpha lead to Inflammation, Proteases cause Basement Membrane Degradation, Degranulation releasing Histmaine, IgE bound to Fc Receptor, B Cells stimulates IgE, Basement Membrane Degradation leads to ECM Damage, Mast Cells begin Degranulation, Il-13 initiate Class-Switching, IgM to IgE, IgE bound to Mast Cells, Basement Membrane Degradation leads to Tissue Damage, Degranulation releasing prostaglandiins, Heparin thins Blood