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This Concept Map, created with IHMC CmapTools, has information related to: Breast Cancer Endpoints - Master Primary, Concepts (e.g. CRF:pCR:Histology) are denoted by solid round-edged rectangle, FDA Criteria for Efficacy endpoints for Breast Cancer treatment has_tumor_information Tumor information, Therapeutic Efficacy Point has Observation or Assessment, Therapeutic Efficacy Point has Therapeutic/Surgical intervention, Survival has_component Progression free survival (PFS), Tumor assessment is_derived_from RECIST v1.1 criteria, Secondary efficacy endpoints (e.g. Overall response rate) are denoted by italics font, Hormone receptor status has_component PR status, Cancer stage has_component M, Cancer stage has_component T, FDA Criteria for Efficacy endpoints for Breast Cancer treatment has_medical_history_information Demographics/Medical history, Overall Survival (OS) starts_concurrent_with Date of Randomization, Primary endpoints has_component Survival, Disease free survival (DFS) ends_concurrent_with Death of any cause, Overall Survival (OS) ends_concurrent_with Death of any cause, Cancer stage has_component N, Repeated concepts/instances are denoted by dotted outline, Survival has_component Overall Survival (OS), Pathologic complete response (pCR) has_pertinent_information CRF: pCR data elements, Disease free survival (DFS) starts_concurrent_with Date of surgery