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This Concept Map, created with IHMC CmapTools, has information related to: Breast Cancer Endpoints - Master Primary m5.3ak, Neoadjuvant setting has_component Overall Survival (OS), Axillary dissection has_status Positive, FDA Criteria for Efficacy endpoints for Breast Cancer treatment has_pertinent_information Tumor Biopsy, Main concept groups (e.g. Primary endpoints) are denoted by Larger bold font with thicker outline, Positive has_follow_up Axillary dissection, Non-measurable lesions has_subtype Cystic lesion, Adjuvant setting has_component Disease free survival (DFS), Progression free survival (PFS) ends_concurrent_with Date of progression, Negative indicates pCR positive, Tumor assessment is_derived_from RECIST v1.1 criteria, FDA Criteria for Efficacy endpoints for Breast Cancer treatment has_pertinent_information Cancer stage, Neoadjuvant setting has_component Pathologic complete response (pCR), Target lesion has_component Quantitative assessment, Demographics/Medical history has_components >Age >Ethnicity >Pregnancy status >BRCA1/2 mutation >Gene expression >Co-morbidities, Concepts (e.g. CRF:pCR:Surgical margins are denoted by solid round-edged rectangle, Positive has_additional _info Extracapsular invasion, Baseline assessment has_pertinent_information Image acquisition, Advanced setting has_component Progression free survival (PFS), Repeated concepts/instances are denoted by dotted outline, Progression validated_by Tumor assessment