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This Concept Map, created with IHMC CmapTools, has information related to: TSP-1, TSP-1 activates TGFbeta1, TSP-1 binds SPARC, CD36, CD47, VEGF, FGF, PDGF, HGF, MMP2, OPG, VEGF mobilization activates VEGFR2 function and expression, TSP-1 upregulates MMP-9 production by pancreatic adenocarcinomas and colon cancer, TGFbeta1 inhibiton decreases osteoclastogenesis, MMP-9 production by pancreatic adenocarcinomas and colon cancer induces Osteoclast differentiation/formation, TGFbeta1 inhibiton prevents osteolysis, TSP-1 upregulates Osteoclast differentiation/formation, MMP-9 production by pancreatic adenocarcinomas and colon cancer inhibits VEGF mobilization, TSP-1 upregulates VEGFR2 function and expression, MMP-9 production by pancreatic adenocarcinomas and colon cancer enhancing Migration, TSP-1 stimulates via CD36 Prostate cancer migration