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This Concept Map, created with IHMC CmapTools, has information related to: GI Week 2, cholesterol excreted predominantly as bile acids, HMG CoA reduced by HMG CoA reductase, Re-synthesis Chylomicron packaging, hypobetalipoproteinemia because chylomicrons and LDL cannot be synthesized, farnesyl pyrophosphate squalene 30C, ABCA1 Increases HDL, Diffusion then Re-synthesis, Cholesterol synthesis occurs in cytosol, Genetic determinants of cholesterol levels APOB, APOB nonsense mutation results in hypobetalipoproteinemia, statins are selective competitive inhibitors for HMG CoA reductase, HMG CoA reductase regulated by hormones, Absorption in the enterocyte by Membrane integration, Vesicle formation/mixed micelle formation Absorption in the enterocyte, Lipids!!!!!!! Get yo' fat! Come get yo' fat! ???? cholesterol, Lipid digestion starts with Lipolysis, Membrane integration then Re-synthesis, Lifestyle control of cholesterol Control LDL through Diet, Diet Contributes to Weight loss, familial hypercholesterolemia because mutation in B-100 --> LDL cannot bind LDLR