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This Concept Map, created with IHMC CmapTools, has information related to: MattReinTutorial, heart rate Increases with positive chronotripic agents, Cardiac Output is directly effected by stroke volume, contractility decreases with negative ionotripes, venous return is directly affected by blood volume, contractility increases with positive ionotropes, Cardiac Output is directly effected by heart rate, preload due to EDV is directly affected by filling time, stroke volume is inversely affected by afterload, heart rate inversely affects filling time, heart rate decreases with negative chronotripic agents, stroke volume is directly affected by contractility, venous return is directly affected by venous pressure, venous return is inversely affected by intrathoracic pressure, stroke volume inversely affects ESV, preload due to EDV is directly affected by venous return, stroke volume is directly affected by preload due to EDV