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This Concept Map, created with IHMC CmapTools, has information related to: Primary Brain Tumors efficacy endpoints v4, MRI has types - With contrast - Without contrast - FLAIR, Surgical Intervention has type Chemotherapy wafers, Enhancing classified as Non-measurable lesions, Sum of the product of all lesions has outcomes -Complete Response (CR) -Partial Response (PR) -Stable disease (SD) -Progression, Histopathology provides evidence for Cellular Classification, Molecular Characteristics determined by Method of detection, perpendicular diameters measured in plane, Present instantiated by - increased - decreased - stable, Regional includes Convection enhanced delivery, Perfusion measured in rCBV, PRIMARY BRAIN TUMORS (HGG) EFFICACY ENDPOINTS include Overall Survival (OS), Enhancing classified as Existing lesion, Sum of the product of all lesions includes Total area of each leasion, Objective Response Rate (ORR) derived from Tumor Response, Repeated concepts/instances throughout the CMAP are denoted by dotted outline, Regional includes Surgical Intervention, Therapeutic Efficacy Endpoint is intersection of Therapeutic Intervention, Qualitative Assessment has attribute - better - same - worse, Surgical Intervention has attributes Extent of surgery, Prior Therapy include Regional