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This Concept Map, created with IHMC CmapTools, has information related to: Mets Brain Tumors efficacy endpoints v7, Target lesion evaluated by Quantitative assessment, Time To Salvage Therapy In the Brain measured by Date of Salvage Therapy, MRI has types - With contrast - Without contrast - FLAIR, Organ specific lesion ID includes - Supratentorial: hemispheric (L, R) - Infratentorial: brain stem cerebellum, Yes instantiated by - Symptoms - Neurocognitive Outcomes - HRQoL - Functional Status, Progression free survival (PFS) has subtypes Non-CNS Lesion, Number of brain metastases instantiated by - single - multiple, Sum of the product of all lesions includes Total area of each leasion, Non-target lesion evaluated by Qualitative Assessment, Status of primary lesion instantiated by - controlled - uncontrolled, Tumor Response is assessed with CT, Regional includes Convection enhanced delivery, METASTATIC BRAIN TUMORS EFFICACY ENDPOINTS include Overall Survival (OS), New lesion identified by Anatomical region, CNS (Brain) Lesion classified as NON-ENHANCING, Objective Response Rate (ORR) derived from Tumor Response, Repeated concepts/instances throughout the CMAP are denoted by dotted outline, Regional includes Surgical Resection, Non-CNS Lesion assesses by RECIST 1.1, Tumor Volume has attribute cm^3