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Deze Concept Map heeft informatie gerelateerd aan: Zonder titel, Mitochondrial dysfunction releases Cytochrome C, Bax, Bak activates Mitochondrial dysfunction, Noxa, Puma activates Mitochondrial dysfunction, p53 ???? Noxa, Puma, E2 UB degradation Beta-catenin, RAS ???? RAF, a-catenine binds Beta-catenin, SMAD4 binds Miz1, Rb supression E2F, CDK2 forms S-CDK complex, Growth Factor Receptors NF-kB Bcl-2, Bcl-XL, c-Myc suppression p15, Proteolytic cascade induces apoptose, Transcription genes ???? c-Myc, PG binds a-catenine, MDM2 binds Ubiquitin, Serine/thereonine kinase receptor phosphorylation SMAD2/3, TGF-beta binds Serine/thereonine kinase receptor, Cycline E/A forms S-CDK complex, CDK4/6 forms G1-CDK complex