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This Concept Map, created with IHMC CmapTools, has information related to: CMap Celbio, Mitochondrium hierdoor komt vrij SMAC, SOS/GEF activeert RAS-GTP, Caspase 3 en caspase 7 activeren Apoptose, BID na knippen tBID, TGF-beta-I fosforyleert SMAD2, RTK activeert lrs 1, VEGF A bindt aan VEGFR 2, Pro caspase 10 en pro caspase 8 maakt Caspase 10 en caspase 8, Cytochroom C Vormt complex Apoptosoom, cycline B activeert M-fase, C-myc synthetiseert C-myc-eiwit, XIAP inhibeert Caspase 3 en caspase 7, Pten defosforyleert PIP 2, actief BH3 only eiwit Inhibeert BAX en BAK, LEF-1 transcribeert Cyclin D1, BCL-2, BCL- XI of MCL1 Inhibeert tBID, MDM2 inhibeert P53, RAS-GTP defosforyleert RAS-GDP, P21 inhibeert cycline B, PIP 2 fosforyleert PIP 3