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This Concept Map, created with IHMC CmapTools, has information related to: Case 2 - Drugs, Calculations ???? The toxic dose of Flunixin Meglumine - 22mL Pre-op drug volume - 10mL Post-op drug volume - 10mL Therefore, the toxic dose was not given to this animal The toxic dose for Pencillin Procaine G - 108mL Pre-op drug volume - 35mL Post-op drug volume - 35mL Therefore, the toxic dose was not given to this animal, Calculations include Flunixin Meglumine (Weight - 500lb cow) Volume (mL) = Dose (mg/kg) x weight (kg) / concentration (mg/mL) Toxic dose - 2.2mL/kg 2.2mg/kg x 500kg / 50mg/mL = 22mL Dose to be used 1mg/kg x 500kg / 50mg/mL = 10mL, Pre-Operative Drugs includes Restraint (M/O), Post-Operative Drugs consider Calculations, Antibiotics such as Procaine Penicillin G (M/O), Calculations ???? The toxic dose of Flunixin Meglumine - 22mL Pre-op drug volume - 10mL Post-op drug volume - 10mL Therefore, the toxic dose was not given to this animal The toxic dose for Pencillin Procaine G - 108mL Pre-op drug volume - 35mL Post-op drug volume - 35mL Therefore, the toxic dose was not given to this animal, Pre-Operative Drugs includes Antibiotics, Post-Operative Drugs includes Antibiotics, Local Anaesthesia (M/O) includes Ring block (M/O), Pre-Operative Drugs be aware of Post-Operative Drugs, Pre-Operative Drugs includes Local Anaesthesia (M/O), Calculations include Flunixin Meglumine (Weight - 500lb cow) Volume (mL) = Dose (mg/kg) x weight (kg) / concentration (mg/mL) Volume to be used 1mg/kg x 500kg / 50mg/mL = 10mL Toxic dose - 2.2mL/kg 2.2mg/kg x 500kg / 50mg/mL = 22mL, Pre-Operative Drugs be aware of The toxic dose of Flunixin Meglumine - 22mL Pre-op drug volume - 10mL Post-op drug volume - 10mL Therefore, the toxic dose was not given to this animal The toxic dose for Pencillin Procaine G - 108mL Pre-op drug volume - 35mL Post-op drug volume - 35mL Therefore, the toxic dose was not given to this animal, Analgesia such as Flunixin meglumine /M/O), DRUGS (Teat Laceration) to manage this case there must be a working knowledge of ASA Grade (M/O), Calculations include Procaine Penicillin G (Weight - 500lb cow) Volume (mL) = Dose (mg/kg) x weight (kg) / concentration (mg/mL) Dose (IU/kg) - 21,000 Standard bottle (US) - 300,000 IU/100 mL Convert IU to mg "Penicillin contains 1,670 International Units (IU) per mg, with limits of error (P = 0.05) of 1,666-1,674 IU/mg." - Hymphrey, Mussett, Perry (1953) Volume to be used 1670 IU Penicillin = 1mg Penicillin 21,000 IU = 12.6mg = 12.6mg/kg x 500kg / (300,000/1670) = 12.6mg/kg x 500kg / 180mg/mL = 35mL Toxic dose 66,000 IU = (66,000/1670) = 39mg 39mg/kg x 500kg / 180mg/ mL = 108mL, Flunixin meglumine /M/O) given SID for 3 days, Procaine Penicillin G (M/O) given BID for 3 days, Analgesia such as Flunixin meglumine (M/O), DRUGS (Teat Laceration) to manage this case there must be a working knowledge of Pre-Operative Drugs