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This Concept Map, created with IHMC CmapTools, has information related to: Robert Dillon D-2, Type 4 hypersensitivity Reaction include reactions such as Stevens-johnson syndrome, Bradykinin causes vasodilation as well as stimulates primary sensory neurons and provokes the release of substance P, neurokin and calcitonin gene-related related peptide eventually leading to Muscle pain, Type 2 hypersensitivity Reaction include autoimmune disorders such as Myasthenia Gravis, Complement C3a and C5a stimulate cytokine production which effects cause Fever, Histoplasmosis include reactions such as Stevens-johnson syndrome, Mast Cells degranulate and release histamine, tryptase and leukotrienes leading to Inflammation, Immediate hypersensitivity reactions Are further subdivided into 3 different reactions due to how the immune system receives and responds to the antigen Type 1 hypersensitivity Reaction, Bradykinin causes vasodilation as well as stimulates primary sensory neurons and provokes the release of substance P, neurokin and calcitonin gene-related related peptide eventually leading to fatigue, Type 4 hypersensitivity Reaction is utilized to see if Ag to tuberculosis exists in patient by injecting tuberculin purified protein derivative aka PPD, Robert Dillon is a 28-year-old Hispanic male, assigned as male at birth and identifies as male, who presents to the clinic with a blistering, painful rash. Robert uses the pronouns he/him/his. Information gathered from the patients history includes Hypotension, Liver Transplant the Graft CD8 T-ce;;s cells may begin attacking the host cells which results in Graft Vs host disease, IgG antigen/antibody complex leads to activation of complement, which attracts various cell types such as: NK cells, TCR is a heterodimer associated with CD3 that must bind to peptide fragments associated with MHC2, Antigen is presented to the bodies immune system and elicits a response Leading to the activation one of the following pathways that include Immediate hypersensitivity reactions, Type 2 hypersensitivity Reaction refers to an antibody-mediated immune reaction directed against cellular or extracellular matrix antigens IgM, MHC2 is expressed on APCs; stabilization by CD28 occurs after recognition by T-Helper cells, Epinephrine is a sympathomimetic drug that works by stimulating both alpha and beta adrenergic receptors leading to bronchial smooth muscle relaxation, vasoconstriction, and decreases mediator release from mast cells which can combat Hypotension, Macrophage first responder to the site of Inflammation, Macrophage are the primary mediatory cells that cause a DTH reaction in the lungs in Histoplasmosis, Robert Dillon is a 28-year-old Hispanic male, assigned as male at birth and identifies as male, who presents to the clinic with a blistering, painful rash. Robert uses the pronouns he/him/his. Information gathered from the patients history includes Sore throat