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This Concept Map, created with IHMC CmapTools, has information related to: Chapter 2 merge revised, Endothelial cells give rise to cancer called Angiosarcoma, Epithelial cells are derived from primitive cell layers called Ectoderm, Distant sites aka Metastases, Tumor cells that are Malignant, Carcinogens cause Human cancers, Specialized cell types e.g. Epithelial cells, Monoclonal are Common, Benign may cause Clinical problems, Carcinomas derived from secretory cells are called Adenocarcinomas, Myelomas express a specific set of genes encoding Immunoglobulin, Carcinogens are not necessarily Mutagens, Specialized cell types e.g. Cells in nervous system, Connective tissue cells are derived from Mesoderm, Pathogensis aka Disease development, Common as evidenced by Barrr odies, Polyclonal are derived from Several different tumor cells, Epithelial- mesenchymal transition may accompany and enable Invasion, Extracellular matrix e.g. Basement membrane, Minor groups that include Melanomas, Carcinogenic can induce Cancers