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This Concept Map, created with IHMC CmapTools, has information related to: Section 6.4, Grb2 are adaptor proteins, growth factor receptor activates Shc, Ras signaling cascade occurs when growth factor receptor, SH3 groups that bind to Sos, Shc activates Grb2, Grb2 activates Sos, Grb2 contains one SH2 group, Shc are adaptor proteins, growth factor receptor activates Grb2, adaptor proteins present in the cytoplasm, SH2 group that binds to the growth factor receptor, Grb2 contains two SH3 groups, Sos are adaptor proteins, Sos activates Ras